Name: Human IMPA2/IMPase 2 Recombinant Protein (His Tag)

Synonyms: Inositol Monophosphatase 2;IMP 2;IMPase 2;Inositol-1(or 4)-Monophosphatase 2;Myo-Inositol Monophosphatase A2;IMPA2;IMP.18P

Expression host: E.coli

Sequence: Met 1-Lys288

Accesstion: O14732

Species: Human

Mol_Mass: 33.5 kDa

AP_Mol_Mass: 30 kDa

Tag: N-His

Purity: > 95 % as determined by reducing SDS-PAGE.


Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 2mM DTT, pH 8.0.

Reconstitution: Not Applicable

Background: Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2′-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.

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