Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by excessive remodeling of small pulmonary arteries, leading to elevated pulmonary vascular resistance and right ventricular failure. Despite advances in therapy,…
Oral squamous cell carcinoma (OSCC) remains a significant global health challenge, with high rates of recurrence and metastasis contributing to poor prognosis. Despite advances in surgical and radiation therapies, the…
Historical Background: The clinical recognition of a form of dementia closely resembling Alzheimer’s disease dates from around 1800. Early descriptions by Pinel and Esquirol documented chronic dementia with symptoms such…
Overweight status is increasingly recognized as a significant health concern beyond its aesthetic implications. It is associated with systemic metabolic disturbances and chronic low-grade inflammation, which may influence the behavior…
Extracellular matrix (ECM) conformation is dynamically regulated by various physiological stimuli, including mechanical forces and allosteric interactions with binding partners. These changes in structure directly influence cellular behavior and function.…