Name: Human HPGDS/GSTS Recombinant Protein
Synonyms: Hematopoietic Prostaglandin D Synthase;H-PGDS;GST Class-Sigma;Glutathione S-Transferase;Glutathione-Dependent PGD Synthase;Glutathione-Requiring Prostaglandin D Synthase;Prostaglandin-H2 D-Isomerase;HPGDS;GSTS;PGDS;PTGDS2
Expression host: E.coli
Sequence: Met 1-Leu199
Accesstion: O60760
Species: Human
Mol_Mass: 22.3 kDa
AP_Mol_Mass: 26 kDa
Tag: None
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, pH 7.0.
Reconstitution: Not Applicable
Background: Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.
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