Name: Human PLA2G16 Recombinant Protein (His Tag)
Synonyms: Group XVI Phospholipase A1/A2;Adipose-Specific Phospholipase A2;AdPLA;H-Rev 107 Protein Homolog;HRAS-Like Suppressor 1;HRAS-Like Suppressor 3;HRSL3;HREV107-1;HREV107-3;Renal Carcinoma Antigen NY-REN-65;PLA2G16;HRASLS3;HREV107
Expression host: E.coli
Sequence: Asp12-Asp132
Accesstion: P53816
Species: Human
Mol_Mass: 14-17 kDa
AP_Mol_Mass: 15 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM EDTA, pH8.0.
Reconstitution: Not Applicable
Background: Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.
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