Name: Human MMP-9 Recombinant Protein (His tag)

Synonyms: Matrix metalloproteinase-9;92 kDa gelatinase;92 kDa type IV collagenase;Gelatinase B;MMP9;CLG4B;GELB;MANDP2

Expression host: HEK293 Cells

Sequence: Met 1-Asp 707

Accesstion: P14780

Species: Human

Mol_Mass: 77.7 kDa

AP_Mol_Mass: 85 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Formulation: Lyophilized from sterile PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein; which is produced by normal alveolar macrophages and granulocytes; can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4; SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; angiogenesis; bone development; wound healing; cell migration; learning and memory; as well as in pathological processes; such as arthritis; intracerebral hemorrhage; and metastasis.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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