Name: Human LYVE1/HAR Recombinant Protein (His Tag)

Synonyms: Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1;LYVE-1;Cell Surface Retention Sequence-Binding Protein 1;CRSBP-1;Extracellular Link Domain-Containing Protein 1;Hyaluronic Acid Receptor;LYVE1;CRSBP1;HAR;XLKD1

Expression host: HEK293 Cells

Sequence: Leu20-Thr 238

Accesstion: AAH26231.1

Species: Human

Mol_Mass: 24.6 kDa

AP_Mol_Mass: 46 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.


Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-Citrate, 150mM NaCl, pH 7.0.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the p

Reconstitution: Please refer to the printed manual for detailed information.

Background: Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

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