Name: Human Leukocyte Ig-Like Receptor B1/ LILRB1/ILT2/CD85j (C-Fc)
Synonyms: Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1;LIR-1;Leukocyte Immunoglobulin-Like Receptor 1;CD85 Antigen-Like Family Member J;Immunoglobulin-Like Transcript 2;ILT-2;Monocyte/Macrophage Immunoglobulin-Like Receptor 7;MIR-7;CD85j;LILRB1;ILT2;LIR1;MIR7
Expression host: HEK293 Cells
Sequence: Gly24-His458
Accesstion: D9IDM8
Species: Human
Mol_Mass: 74.1 kDa
AP_Mol_Mass: 100-120 kDa
Tag: C-Fc
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes,dendritic cells,and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.
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