Name: Human ALDH1A1/ALDC Recombinant Protein (His Tag)
Synonyms: Retinal Dehydrogenase 1;RALDH 1;RalDH1;ALDH-E1;ALHDII;Aldehyde Dehydrogenase Family 1 Member A1;Aldehyde Dehydrogenase Cytosolic;ALDH1A1;ALDC;ALDH1;PUMB10;ALDH11;HEL-9;HEL-S-53e;HEL12;PUMB1;RALDH1
Expression host: E.coli
Sequence: Met 1-Ser501
Accesstion: P00352
Species: Human
Mol_Mass: 57.0 kDa
AP_Mol_Mass: 60 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, 1mM DTT, pH 8.0.
Reconstitution: Not Applicable
Background: Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties and subcellular localizations. ALDH1A1 is the main cytosolic isoform, which has a lower affinity for aldehydes than the mitochondrial enzyme. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid.
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