Name: Human LDH-A/LDHA Recombinant Protein (His Tag)
Synonyms: L-Lactate Dehydrogenase A Chain;LDH-A;Cell Proliferation-Inducing Gene 19 Protein;LDH Muscle Subunit;LDH-M;Renal Carcinoma Antigen NY-REN-59;LDHA
Expression host: E.coli
Sequence: Met 1-Phe332
Accesstion: P00338
Species: Human
Mol_Mass: 38.8 kDa
AP_Mol_Mass: 37 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween80, 1mM EDTA, 50% Glycerol, pH8.0.
Reconstitution: Not Applicable
Background: L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
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