Name: Human LAT2 Recombinant Protein (His Tag)

Synonyms: Linker for Activation of T-Cells Family Member 2;Linker for Activation of B-Cells;Membrane-Associated Adapter Molecule;Non-T-Cell Activation Linker;Williams-Beuren Syndrome Chromosomal Region 15 Protein;Williams-Beuren Syndrome Chromosomal Region 5 Protein;LAT2;LAB;NTAL;WBS15;WBSCR15;WBSCR5

Expression host: HEK293 Cells

Sequence: Arg27-Ala243

Accesstion: Q9GZY6

Species: Human

Mol_Mass: 25.0 kDa

AP_Mol_Mass: 35-40 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.


Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual

Reconstitution: Please refer to the printed manual for detailed information.

Background: Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Coupleing activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

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