Name: Human JAM-B/CD322 Recombinant Protein (His Tag)

Synonyms: Junctional Adhesion Molecule B;JAM-B;Junctional Adhesion Molecule 2;JAM-2;Vascular Endothelial Junction-Associated Molecule;VE-JAM;CD322;JAM2;C21orf43;VEJAM

Expression host: HEK293 Cells

Sequence: Phe29-Asn236

Accesstion: P57087

Species: Human

Mol_Mass: 24.3 kDa

AP_Mol_Mass: 35-39 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.


Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the print

Reconstitution: Please refer to the printed manual for detailed information.

Background: Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28); an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain; a transmembrane segment (aa 239-259); and a cytoplasmic domain (aa 260 – 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart; placenta; lung; foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

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