Name: Human IPPI2/IDI2 Recombinant Protein (His Tag)
Synonyms: Isopentenyl-Diphosphate Delta-Isomerase 2;Isopentenyl Pyrophosphate Isomerase 2;IPP Isomerase 2;IPPI2;IDI2
Expression host: E.coli
Sequence: Met 1-Val227
Accesstion: Q9BXS1
Species: Human
Mol_Mass: 28.9 kDa
AP_Mol_Mass: 28-31 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 0.1mM PMSF, pH 8.0.
Reconstitution: Not Applicable
Background: Isopentenyl Pyrophosphate Isomerase 2 (IDI2) belongs to the IPP isomerase type 1 family. Both isozymes, IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway. IDI2 is expressed in skeletal muscle, which contains one nudix hydrolase domain. IDI2 binds one magnesium per subunit. IDI2 catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). It is reported that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPAR-α.
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