Name: Human AGR2 Recombinant Protein (His Tag)

Synonyms: Anterior Gradient Protein 2 Homolog;AG-2;hAG-2;HPC8;Secreted Cement Gland Protein XAG-2 Homolog;AGR2;AG2

Expression host: HEK293 Cells

Sequence: Arg21-Leu175

Accesstion: O95994

Species: Human

Mol_Mass: 18.9 kDa

AP_Mol_Mass: 18 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.


Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 10%Glycerol, 0.01%Tween80, pH8.0.

Reconstitution: Not Applicable

Background: Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 – 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 – 175, human AGR2 shares 94% aa identity with mouse AGR2.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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