Name: Human Immunoglobulin Superfamily Member 8/IGSF8/CD316 (C-Fc)

Synonyms: Immunoglobulin Superfamily Member 8;IgSF8;CD81 Partner 3;Glu-Trp-Ile EWI Motif-Containing Protein 2;EWI-2;Keratinocytes-Associated Transmembrane Protein 4;KCT-4;LIR-D1;Prostaglandin Regulatory-Like Protein;PGRL;CD316;IGSF8;CD81P3;EWI2;KCT4

Expression host: HEK293 Cells

Sequence: Arg28-Thr579

Accesstion: Q969P0

Species: Human

Mol_Mass: 85.7 kDa

AP_Mol_Mass: 90-120 kDa

Tag: C-Fc

Purity: > 95 % as determined by reducing SDS-PAGE.


Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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