Name: Human Immunoglobulin Superfamily Member 8/IGSF8/CD316 (C-Fc)
Synonyms: Immunoglobulin Superfamily Member 8;IgSF8;CD81 Partner 3;Glu-Trp-Ile EWI Motif-Containing Protein 2;EWI-2;Keratinocytes-Associated Transmembrane Protein 4;KCT-4;LIR-D1;Prostaglandin Regulatory-Like Protein;PGRL;CD316;IGSF8;CD81P3;EWI2;KCT4
Expression host: HEK293 Cells
Sequence: Arg28-Thr579
Accesstion: Q969P0
Species: Human
Mol_Mass: 85.7 kDa
AP_Mol_Mass: 90-120 kDa
Tag: C-Fc
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.
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