Synonyms: Interleukin-20 Receptor Subunit Alpha;IL-20 Receptor Subunit Alpha;IL-20R-Alpha;IL-20RA;Cytokine Receptor Class-II Member 8;Cytokine Receptor Family 2 Member 8;CRF2-8;IL-20R1;ZcytoR7;IL20RA
Expression host: HEK293 Cells
Sequence: Val30-Lys250
Accesstion: Q9UHF4
Species: Human
Mol_Mass: 52.4 kDa
AP_Mol_Mass: 70-85 kDa
Tag: C-Fc
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Interleukin-20 Receptor Subunit α (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide; a 221 amino acid extracellular domain with two fibronectin type-III domains; a 24 amino acid transmembrane region; and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB; and the complex serves as a receptor for IL19; IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.
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