Name: Human IL2RG/CD132 Recombinant Protein (aa 23-262, Fc Tag)
Synonyms: Cytokine receptor common subunit gamma;Interleukin-2 receptor subunit gamma;gammaC;P64;CD132;IL2RG;SCIDX;SCIDX1;CIDX
Expression host: HEK293 Cells
Sequence: Leu23-Ala262
Accesstion: P31785
Species: Human
Mol_Mass: 55.4 kDa
AP_Mol_Mass: 85-100 kDa
Tag: C-Fc
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors; including those of interleukin -2; -4; -7 and -21; and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).
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