Name: Human Hepcidin/HAMP Recombinant Protein (GST Tag)

Synonyms: Liver-expressed antimicrobial peptide 1;Putative liver tumor regressor;HEPC;LEAP1

Expression host: E.coli

Sequence: Asp60-Thr84

Accesstion: P81172

Species: Human

Mol_Mass: 29.2 kDa

AP_Mol_Mass: 28-30 kDa

Tag: N-GST

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4.

Reconstitution: Not Applicable

Background: Hepcidin(HAMP)is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.

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