Name: Human Glucagon/GCG Recombinant Protein (His Tag)
Synonyms: Glucagon;Glicentin;Glicentin-Related Polypeptide;GRPP;Oxyntomodulin;OXM;OXY;Glucagon;Glucagon-Like Peptide 1;GLP-1;Incretin Hormone;Glucagon-like Peptide 1;GLP-1;Glucagon-Like Peptide 2;GLP-2;GCG
Expression host: HEK293 Cells
Sequence: Arg21-Lys180
Accesstion: P01275
Species: Human
Mol_Mass: 18.6 kDa
AP_Mol_Mass: 19 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 1mM DTT, 50% Glycerol, pH 8.0.
Reconstitution: Not Applicable
Background: Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. In the glucagon antagonist, His-53 and Phe-58 are missing. This antagonist has been successfully utilized to reduce glucose concentration in vivo.
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