Name: Human GGCT Recombinant Protein (His Tag)
Synonyms: Gamma-Glutamylcyclotransferase;Cytochrome C-Releasing Factor 21;GGCT;C7orf24;CRF21
Expression host: E.coli
Sequence: Met 1-Leu188
Accesstion: O75223
Species: Human
Mol_Mass: 23.2 kDa
AP_Mol_Mass: 24-30 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
Reconstitution: Not Applicable
Background: Human Υ-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.
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