Name: Human Gankyrin/PSDM10 Recombinant Protein

Synonyms: 26S Proteasome Non-ATPase Regulatory Subunit 10;26S Proteasome Regulatory Subunit p28;Gankyrin;p28(GANK);PSMD10

Expression host: E.coli

Sequence: Met 1-Gly226

Accesstion: O75832

Species: Human

Mol_Mass: 24.4 kDa

AP_Mol_Mass: 26 kDa

Tag: None

Purity: > 95 % as determined by reducing SDS-PAGE.


Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Reconstitution: Not Applicable

Background: Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites:
Popular product recommendations:
P-Selectin Protein
Complement C5/C5a Protein
Popular categories:
IFN-alpha 14
Ubiquitin-Specific Peptidase 28