Name: Human GALK1/Galactokinase Recombinant Protein (His Tag)
Synonyms: Galactokinase;Galactose Kinase;GALK1;GALK
Expression host: E.coli
Sequence: Met1-Leu392
Accesstion: P51570
Species: Human
Mol_Mass: 43.3 kDa
AP_Mol_Mass: 45 kDa
Tag: C-His
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus; a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose; which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II; an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.
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