Product Name :
Rabbit anti-SERBP1 Polyclonal Antibody(Center)

Synonym :
Plasminogen activator inhibitor 1 RNA-binding protein; PAI1 RNA-binding protein 1; PAI-RBP1; SERPINE1 mRNA-binding protein 1; SERBP1; PAIRBP1

Host :
Rabbit

Species Reactivity:
Human, Mouse, Rat

Specificity :
This SERBP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-183 amino acids from the Central region of human SERBP1.

Predicted Reactivity:

Applications :
WB~~1:1000

Immunogen:

Concentration :

Purification :

Clonality:
Polyclonal Antibody

Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long time storage store at -20 ° C in small aliquots to prevent free that cycles

Research areas :
Cancer;Crown Antibodies

Background :
May play a role in the regulation of mRNA stability. Binds to the 3′-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.

UniProt :
Q8NC51

Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Purified Rabbit Polyclonal Antibody (Pab) |Synonym Plasminogen activator inhibitor 1 RNA-binding protein; PAI1 RNA-binding protein 1; PAI-RBP1; SERPINE1 mRNA-binding protein 1; SERBP1; PAIRBP1 |Host Rabbit |Specificity This SERBP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-183 amino acids from the Central region of human SERBP1. |Species Reactivity Human, Mouse, Rat |Applications WB~~1:1000 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long time storage store at -20 ° C in small aliquots to prevent free that cycles |Research areas Cancer;Crown Antibodies |Target |Background May play a role in the regulation of mRNA stability. Binds to the 3′-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. |Cellular localization Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Also found in perinuclear regions |UniProt Q8NC51 |References |References Lai C.-H.,et al.Genome Res. 10:703-713(2000).Wiemann S.,et al.Genome Res. 11:422-435(2001).Ota T.,et al.Nat. Genet. 36:40-45(2004).Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Gregory S.G.,et al.Nature 441:315-321(2006). |Tips:This product is for research use only. Not for use in diagnostic prodcedures.

Rabbit anti-SERBP1 Polyclonal Antibody(Center)

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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