Name: Human DTD1 Recombinant Protein (His Tag)
Synonyms: D-tyrosyl-tRNA(Tyr) deacylase 1;DNA-unwinding element-binding protein B;DUE-B;Histidyl-tRNA synthase-related;DTD1;C20orf88;DUEB;HARS2
Expression host: HEK293 Cells
Sequence: Met 1-Pro209
Accesstion: Q8TEA8
Species: Human
Mol_Mass: 24.5 kDa
AP_Mol_Mass: 30 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Not Applicable
Background: D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.
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