Name: Human CRADD/RAIDD Recombinant Protein
Synonyms: Death Domain-Containing Protein CRADD;Caspase and RIP Adapter with Death Domain;RIP-Associated Protein with A Death Domain;CRADD;RAIDD
Expression host: E.coli
Sequence: Met1-Glu199
Accesstion: P78560
Species: Human
Mol_Mass: 23 kDa
AP_Mol_Mass: 21 kDa
Tag: None
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed man
Reconstitution: Please refer to the printed manual for detailed information.
Background: Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues; with particularly high expression in the adult heart; testis; liver; skeletal muscle; fetal liver; and kidney. CRADD contains one CARD domain that mediates the interaction with Caspase-2; and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for Caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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