Name: Human HGPRT/HPRT1 Recombinant Protein (His Tag)
Synonyms: Hypoxanthine-Guanine Phosphoribosyltransferase;HGPRT;HGPRTase;HPRT1;HPRT
Expression host: E.coli
Sequence: Met 1-Ala218
Accesstion: P00492
Species: Human
Mol_Mass: 27.8 kDa
AP_Mol_Mass: 29 kDa
Tag: N-His
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 250mM NaCl, 50% Glycerol, pH8.0.
Reconstitution: Not Applicable
Background: Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed purine synthesis, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.
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