Product Name :
Rabbit anti-GRIN2A Polyclonal Antibody
Synonym :
EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A
Host :
Rabbit
Species Reactivity:
Mouse, Rat
Specificity :
Predicted Reactivity:
Applications :
WB 1:500 – 1:1000IHC 1:50 – 1:200
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1130-1400 of human GRIN2A (NP_000824.1).
Concentration :
Purification :
Affinity purification
Clonality:
Polyclonal Antibody
Storage Temp.:
Store at -20 ℃Avoid freeze / that cycles
Research areas :
Background :
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
UniProt :
Q12879
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A |Host Rabbit |Species Reactivity Mouse, Rat |Applications WB 1:500 – 1:1000IHC 1:50 – 1:200 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1130-1400 of human GRIN2A (NP_000824.1). |Positive control Mouse brain,Rat brain |Properties |Purification Affinity purification |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. |Cellular localization Cell junction,Cell membrane,Multi-pass membrane protein,postsynaptic cell membrane,synapse |UniProt Q12879 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-GRIN2A Polyclonal Antibody
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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