Name: Human Dipeptidase 1/DPEP1 Recombinant Protein (His Tag)
Synonyms: Dipeptidase 1;Dehydropeptidase-I;Microsomal Dipeptidase;Renal Dipeptidase;hRDP;DPEP1;MDP;RDP;MBD1
Expression host: HEK293 Cells
Sequence: Asp17-Ser385
Accesstion: P16444
Species: Human
Mol_Mass: 42.1 kDa
AP_Mol_Mass: 41 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
Reconstitution: Not Applicable
Background: Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics; such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However; DPEP1 expression decreased with pathological differentiation; lymph-node and distant metastasis.
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