Name: Human Cyclophilin D/PPID Recombinant Protein (His Tag)
Synonyms: Peptidyl-Prolyl Cis-Trans Isomerase D;PPIase D;40 kDa Peptidyl-Prolyl Cis-Trans Isomerase;Cyclophilin-40;CYP-40;Cyclophilin-Related Protein;Rotamase D;PPID;CYP40;CYPD
Expression host: E.coli
Sequence: Met 1-Ala370
Accesstion: Q08752
Species: Human
Mol_Mass: 43.9 kDa
AP_Mol_Mass: 40 kDa
Tag: N-His & C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
Reconstitution: Not Applicable
Background: Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.
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