Name: Human FKBP4 Recombinant Protein (His Tag)
Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP4;51kDa FK506-binding protein;51kDa FK506-binding protein;59kDa immunophilin;FK506-binding protein 4;FKBP59;HSP-binding immunophilin;immunophilin FKBP52;Rotamase;FKBP4
Expression host: E.coli
Sequence: Met 1-Ala459
Accesstion: Q02790
Species: Human
Mol_Mass: 52.8 kDa
AP_Mol_Mass: 50-60 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.
Reconstitution: Not Applicable
Background: FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
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