Name: Human dUTPase Recombinant Protein (His Tag)

Synonyms: Deoxyuridine 5′-Triphosphate Nucleotidohydrolase Mitochondrial;dUTPase;dUTP Pyrophosphatase;DUT

Expression host: E.coli

Sequence: Glu94-Asn252

Accesstion: P33316-2

Species: Human

Mol_Mass: 20.0 kDa

AP_Mol_Mass: 20 kDa

Tag: N-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Reconstitution: Not Applicable

Background: Deoxyuridine 5′-Triphosphate Nucleotidohydrolase Mitochondrial (dUTPase) belongs to the dUTPase family. dUTPase exits as a homotrimer and is involved in nucleotide metabolism. dUTPase produces dUMP; the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. The dUTPase increase in PCR product yield; length and fidelity enables further down-stream applications. These effects make dUTPase useful in PCR fidelity and yield-sensitive applications. dUTPase is specific for dUTP and is critical for the fidelity of DNA replication and repair.

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