Name: Human ATG4A Recombinant Protein (His Tag)
Synonyms: Cysteine Protease ATG4A;AUT-Like 2 Cysteine Endopeptidase;Autophagin-2;Autophagy-Related Cysteine Endopeptidase 2;Autophagy-Related Protein 4 Homolog A;hAPG4A;ATG4A;APG4A;AUTL2
Expression host: E.coli
Sequence: Met 1-Val398
Accesstion: Q8WYN0
Species: Human
Mol_Mass: 47.5 kDa
AP_Mol_Mass: 40-55 kDa
Tag: N-His
Purity: > 80 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Not Applicable
Background: Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
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