Name: Human UBE2A Recombinant Protein (GST & His Tag)
Synonyms: Ubiquitin-Conjugating Enzyme E2 A;RAD6 Homolog A;HR6A;hHR6A;Ubiquitin Carrier Protein A;Ubiquitin-Protein Ligase A;UBE2A;RAD6A
Expression host: E.coli
Sequence: Met 1-Cys152
Accesstion: P49459
Species: Human
Mol_Mass: 49.0 kDa
AP_Mol_Mass: 45 kDa
Tag: N-GST-His
Purity: > 80 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes; or E1s; ubiquitin-conjugating enzymes; or E2s; and ubiquitin-protein ligases; or E3s. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is required for postreplication repair of UV-damaged DNA. UBE2A Interacts with RAD18 and WAC.
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