Name: Human PLA2G7/Lp-PLA2 Recombinant Protein (His Tag)

Synonyms: 2-acetyl-1-alkylglycerophosphocholine esterase;EC 3.1.1;EC;1-alkyl-2-acetylglycerophosphocholine esterase;Group-VIIA phospholipase A2;gVIIA-PLA2;LDL-associated phospholipase A2;LDL-PLA(2);LDL-PLA2;lipoprotein-associated phospholipase A2;LpPLA2;Lp-PLA2;PAF acetylhydrolase;PAF-AH;PAFAHPAF 2-acylhydrolase;phospholipase A2;group VII (platelet-activating factor acetylhydrolase;PLA2G7;plasma);platelet-activating factor acetylhydrolase

Expression host: HEK293 Cells

Sequence: Phe22-Asn441

Accesstion: AAH38452.1

Species: Human

Mol_Mass: 48.8 kDa

AP_Mol_Mass: 50-65 kDa

Tag: C-His

Purity: > 90 % as determined by reducing SDS-PAGE.


Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 50mM NaAc, 150mM NaCl, 50% Glycerol, pH5.0.

Reconstitution: Not Applicable

Background: Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presence of inflammatory bodily responses. PAFAH alters the action of PAF by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PAFAH has specificity for substrates with a short residue at the sn-2 position.

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