Name: Human PDAP1/PAP Recombinant Protein (His Tag)

Synonyms: 28 kDa Heat- and Acid-Stable Phosphoprotein;PDGF-Associated Protein;PAP;PDGFA-Associated Protein 1;PAP1;PDAP1;HASPP28

Expression host: E.coli

Sequence: Met 1-Lys181

Accesstion: Q13442

Species: Human

Mol_Mass: 22.8 kDa

AP_Mol_Mass: 30 kDa

Tag: N-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 0.1mM PMSF, 2mM DTT, pH 8.0.

Reconstitution: Not Applicable

Background: Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-Associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.

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