Name: Human Ketohexokinase/KHK Recombinant Protein (His Tag)
Synonyms: Ketohexokinase;Hepatic fructokinase;KHK
Expression host: HEK293 Cells
Sequence: Met 1-Val298
Accesstion: AAH06233.1
Species: Human
Mol_Mass: 33.7 kDa
AP_Mol_Mass: 30 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50nM KCl, 10% Glycerol, pH 7.4.
Reconstitution: Not Applicable
Background: Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.This enzyme catalyzes conversion of fructose to fructose-1-phosphate. It is the first enzyme with a specialized pathway that catabolizes dietary fructose. Defects in KHK are the cause of fructosuria.
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