Name: Human Kallikrein 11/KLK11 Recombinant Protein (His Tag)

Synonyms: Kallikrein-11;hK11;Hippostasin;Serine Protease 20;Trypsin-Like Protease;KLK11;PRSS20;TLSP

Expression host: HEK293 Cells

Sequence: Glu19-Asn250

Accesstion: AAH22068

Species: Human

Mol_Mass: 26.3 kDa

AP_Mol_Mass: 38 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.


Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, pH 8.0.

Reconstitution: Not Applicable

Background: Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide;a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

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