Tatus quo or worsened after treatment: De la Fuente 1994. Barrett Impulsiveness Scale (BIS): Soloff 1989; Soloff 1993. Behavioural reports of numbers of episodes of impulsivityaggressive behaviour: Soler 2005. Borderline Character Disorder Severity Index (BPDSI), subscale “impulsivity”: Rinne 2002. CGI-BPD, subscale “impulsivity”: Bogenschutz 2004; Pascual 2008. Modified Overt Aggression Scale (MOAS), total score:Frankenburg 2002; Zanarini 2003. Overt Aggression Scale-Modified (OAS-M), subscale “aggression”: Hollander 2001; Simpson 2004. Stait-Trait Anger Expression Inventory (STAXI), subscale “anger out”: Nickel 2004 and Nickel 2005; Nickel 2006; Tritt 2005. ZAN-BPD, subscale “impulsivity which might be self-damaging”:Reich 2009; Schulz 2007; Zanarini 2007.(e) (f) (g)(h) (i)Cochrane Database Syst Rev. Author manuscript; out there in PMC 2014 September 21.Stoffers et al.Web page(6) Suicidal behavioursuicidal ideation (a) (b) Behavioural reports of numbers of episodes of self-injuring behavioursuicide attempts: Soler 2005. CGI-BPD, subscale “recurrent suicidal ideation”: Bogenschutz 2004; Pascual 2008. OAS-M, subscale “suicidality”: Hallahan 2007; Hollander 2001; Simpson 2004. OAS-M, subscale “suicidality”: quantity of patients with high suicidality, i.e. frequent suicide ideation andor planning or behaviour: Linehan 2008. Ratio of patients with suicidal act in the course of treatment:Montgomery 197982; Montgomery 818283. ZAN-BPD, subscale “suicidal or self-mutilating behaviour”:Schulz 2007; Zanarini 2007.Verubecestat Europe PMC Funders Author Manuscripts Europe PMC Funders Author Manuscripts(c) (d) (e) (f)(7) Self-injurious behaviour (a) (b) Ratio of individuals with self-injury throughout treatment period:Hallahan 2007; Linehan 2008; Nickel 2006. OAS-M, subscale “auto aggression”: Simpson 2004.(8) Affective instability (a) (b) (c) BPDSI, subscale “rapid mood shifts”: Rinne 2002. CGI-BPD, subscale “affective instability”: Bogenschutz 2004;Pascual 2008. ZAN-BPD, subscale “affective instability”: Reich 2009; Schulz 2007; Zanarini 2007.(9) Chronic feelings of emptiness (a) CGI-BPD, subscale “chronic feelings of emptiness”:Bogenschutz 2004; Pascual 2008. ZAN-BPD, subscale “chronic feelings of emptiness”: Schulz 2007; Zanarini 2007.(b)(10) Inappropriate anger (a) (b) (c) BPDSI, subscale “anger”: Rinne 2002. CGI-BPD, subscale “inappropriate anger”: Bogenschutz 2004;Pascual 2008. HSCL, SCL-90 or SCL-90-R, subscale “hostility”: De la Fuente 1994; Frankenburg 2002; Goldberg 1986; Loew 2006; Nickel 2006; Soloff 1989; Soloff 1993; Zanarini 2001. OAS-M, subscale “irritability”: Hollander 2001. Profile of Mood States (POMS), subscale “anger”: Salzman 1995.(d) (e)Cochrane Database Syst Rev. Author manuscript; accessible in PMC 2014 September 21.Stoffers et al.Page(f) (g)STAXI, subscale “trait anger”: Nickel 2004 and Nickel 2005;Tritt 2005. ZAN-BPD, subscale “intense anger”: Schulz 2007; Zanarini 2007.(11) Psychoticparanoid symptoms or dissociation (a) CGI-BPD, subscale “transient paranoia or dissociation”:Bogenschutz 2004; Pascual 2008. Dissociative Experiences Scale (DES): Simpson 2004. HSCL, SCL-90 or SCL-90-R, subscale “paranoid ideation”:De la Fuente 1994; Loew 2006; Nickel 2006; Soloff 1989; Soloff 1993. SIB, subscale “suspiciousparanoid”: Goldberg 1986. ZAN-BPD, subscale “paranoid ideation of dissociation”:Schulz PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21353699 2007; Zanarini 2007.Europe PMC Funders Author Manuscripts Europe PMC Funders Author Manuscripts(b) (c) (d) (e)Secondary outcomes (1) Depression (a) (b) (c) (d) BDI: Hallahan.